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BioData Catalyst home

NHLBI BioData Catalyst® (BDC)

Explore data. Run analyses. Advance science.

BDC brings together rich longitudinal, phenotypic, and genomic data, so researchers can discover, combine, and analyze data at scale without managing complex infrastructure.

Learn About BDC

Why BDC?

Ask Questions Across Datasets

Build on decades of research

Access well-characterized data from longstanding NHLBI studies and programs.

Connect data in new ways

Bring together information across studies, cohorts, phenotypes, and genomic resources to ask questions beyond a single dataset.

Analyze without building the infrastructure

Use secure, scalable cloud environments and reusable analytical resources alongside the data.

Data in BDC

Explore the Breadth of BDC-Hosted Data

Longitudinal &
Epidemiologic Data

Long-running cohort and observational studies with repeated measures over time

Phenotypic &
Clinical Data

Detailed health, behavioral, environmental, and clinical characterization

Genomic &
Omics Data

Whole-genome sequencing and complementary molecular data

Specialized HLBS Data

Imaging, sleep, physiological, and disease-specific research data

Connect data across studies and data types to ask questions that extend beyond a single dataset.

Explore BDC Data
Breadth & Scale

A growing resource with broad coverage and deep scientific value.

500+
Hosted Datasets
39%
Multi-modal datasets
26
Distinct data types
5+
petabytes of data

Start Your Research Journey

BDC helps researchers move from finding a relevant study to asking questions across multiple datasets. Explore NHLBI data, identify studies or cohorts that fit your research question, and move directly into secure cloud environments where data can be analyzed individually or together.

BDC supports the research process from data discovery and access through analysis, collaboration, reproducibility, and publication.

Cloud Credits may be available for you to get started.  Learn about usage costs and cloud credits.

  1. Explore data

    Search NHLBI studies and explore available variables and datasets before signing in.

    Explore data »

  2. Confirm or request access

    Use your eRA Commons account to access approved datasets or submit a dbGaP request.

    Check Access »

  3. Analyze securely

    Bring scalable computing to the data and analyze datasets individually or together in secure cloud workspaces.

    Analyze Data »

  4. Advance and share research

    Collaborate, reproduce analyses, and share findings others can build upon.

    View BDC-Enabled Research »
Need help with BDC? Submit a request .

Featured Initatives

Researcher-Focused Initiatives

Discover how BDC works with research initiatives to support researchers, improve their experience in the ecosystem, and advance data-driven research.

TOPMed

The NHLBI Trans-Omics for Precision Medicine program integrates whole-genome sequencing and other omics data with clinical, behavioral, imaging, environmental, and molecular data to advance precision medicine for heart, lung, blood, and sleep disorders.

Precision Medicine

112 datasets

RECOVER

RECOVER data in BDC includes longitudinal cohort, electronic health record, pathobiology, tissue pathology, wearable and clinical trial data supporting research into Long COVID across adult and pediatric populations.

Long COVID & PASC

3 datasets

National Sleep Research Resource (NSRR)

NSRR data in BDC includes polysomnography, actigraphy, and questionnaire data from cohorts, clinical trials, and other sources, supporting secondary research in sleep and circadian science.

Sleep and Circadian Rhythms

7 datasets

Heartshare

HeartShare data in BDC includes phenotypic, imaging, and omics data from people with heart failure with preserved ejection fraction (HFpEF) and controls, including baseline and longitudinal data.

Cardiovascular

54 datasets

View all Researcher-Focused Initiatives

Latest Publications

View all publications »

Research in Action

See what researchers are discovering with BDC. Explore recent publications that use BDC data, computing resources, and analytical tools to answer scientific questions.

Recent Publication

Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

Published in Diabetes on Jun 11, 2026

View Publication

Recent Publication

Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3

Published in Journal of Cachexia, Sarcopenia and Muscle on Apr 23, 2026

View Publication

Learning & Training

Training Opportunities with BDC

Give students and emerging researchers hands-on experience with real-world biomedical data science without requiring institutions to build specialized computational infrastructure.

Explore BDC for Learning and Training
Cloud Credits may be available for courses and training.
Learn more.

Latest from BDC

View all news »

What's Happening

News

Published · Jul 1, 2026

July 2026 BDC Newsletter

Read the latest BDC newsletter, including recent ecosystem news, data updates, events, training opportunities, and reminders for the BDC community. This newsletter opens in Mailchimp.

View full update

Researcher Perspectives

What BDC Researchers Are Saying

BDC allows you to do analyses effortlessly and has the infrastructure set up for you.
- Brandon Lê, Researcher, Duke University

Ready to Work in BDC?

Get help finding data or using our secure cloud workspace.

Get Help Documentation